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5-(4-fluorophenyl)-1,3,8,8-tetramethyl-8,9-dihydro-1H-chromeno[2,3-d]pyrimidine-2,4,6(3H,5H,7H)-trione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1257244-45-3

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1257244-45-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1257244-45-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,7,2,4 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1257244-45:
(9*1)+(8*2)+(7*5)+(6*7)+(5*2)+(4*4)+(3*4)+(2*4)+(1*5)=153
153 % 10 = 3
So 1257244-45-3 is a valid CAS Registry Number.

1257244-45-3Downstream Products

1257244-45-3Relevant academic research and scientific papers

Multicomponent synthesis of some benzo, pyrimido and pyrazolo fused heterocycles using [Nmp]H2Po4 as an efficient reaction medium

Kumari, Sudesh,Khurana

, p. 395 - 404 (2019/01/21)

An efficient synthesis of benzoxanthene, pyrimidoquinoline, pyrimidochromene and pyrazolopyridine fused heterocycles by condensation of aromatic aldehydes, 2- hydroxy-1,4-naphthoquinone/ 6-amino-1,3-dimethyl uracil/ 1,3-dimethyl barbituric acid/ 5-amino-3-methyl-1-phenylpyrazole and 5,5-dimethylcyclohexane-1,3-dione/5- methylcyclohexane-1,3-dione/ cyclohexane-1,3-dione/cyclopentane-1,3-dione has been developed using [NMP]H2PO4 as a highly efficient reaction medium and catalyst. All the reactions proceeded smoothly and gave corresponding products in high yield after a simple workup.

Application of cyclic-1,3-diketones in domino and multicomponent reactions: Facile route to highly functionalized chromeno[2,3-d]pyrimidinones and diazabenzo[b]fluorenones under solvent-free conditions

Kumar, Ram,Raghuvanshi, Keshav,Verma, Rajiv K.,Singh, Maya S.

scheme or table, p. 5933 - 5936 (2010/11/21)

A facile and efficient protocol for the synthesis of chromeno[2,3-d] pyrimidinones and diazabenzo[b]fluorenones has been developed by one-pot three-component cyclocondensation of aldehydes, cyclic-1,3-diketones and 1,3-dimethylbarbituric acid in the presence of InCl3 or P 2O5 under solvent-free conditions.

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