1257326-23-0

Basic information

• Product Name: (N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine
• Synonyms: (N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine;NPEC-caged-dopamine;PDNNZLULXSQJGZ-UHFFFAOYSA-N
• CAS NO: 1257326-23-0
• Molecular Formula: C17H18N2O6
• Molecular Weight: 346.33462
• Mol File: 1257326-23-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Store at -20°C
• CAS DataBase Reference: (N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine(1257326-23-0)
• EPA Substance Registry System: (N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine(1257326-23-0)

Safety Data

• Hazardous Substances Data: 1257326-23-0(Hazardous Substances Data)

Usage

Description

(N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine, also known as NPEC-caged-dopamine, is a caged compound derived from the combination of dopamine and a nitrophenylethylcarboxy group. It is characterized by its ability to release dopamine upon exposure to UV light, which leads to the activation of D1 receptors. This unique property makes it a promising candidate for various applications in the pharmaceutical industry.

Uses

Used in Pharmaceutical Synthesis:
NPEC-caged-dopamine is used as a building block for the synthesis of various pharmaceuticals. Its ability to release dopamine upon UV light illumination makes it a valuable component in the development of drugs targeting D1 receptor activation.
Used in Drug Delivery Systems:
In the field of drug delivery, NPEC-caged-dopamine can be employed as a component in the design of controlled-release systems. By incorporating this caged compound into a drug delivery platform, it is possible to achieve targeted and controlled release of dopamine, which can be particularly useful in treating conditions that require precise dopamine modulation.
Used in Neuroscience Research:
NPEC-caged-dopamine is also used as a research tool in neuroscience. The ability to control dopamine release with UV light allows researchers to study the effects of dopamine on D1 receptors in a more controlled and precise manner, which can lead to a better understanding of dopamine-related neurological processes and the development of new treatments for related disorders.
Used in Optogenetics:
In the field of optogenetics, NPEC-caged-dopamine can be utilized to control the activity of D1 receptor-expressing cells. By combining this caged compound with genetically modified cells that express D1 receptors, researchers can selectively activate these cells using UV light, providing valuable insights into cellular signaling and function.