1257398-99-4

Basic information

• Product Name: (2S,3R,4R)-4-(4-benzylpiperidin-1-yl)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)-5-methylenetetrahydrofuran-3-ol
• CAS NO: 1257398-99-4
• Molecular Weight: 373.492
• Mol File: 1257398-99-4.mol

Chemical Properties

• CAS DataBase Reference: (2S,3R,4R)-4-(4-benzylpiperidin-1-yl)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)-5-methylenetetrahydrofuran-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4R)-4-(4-benzylpiperidin-1-yl)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)-5-methylenetetrahydrofuran-3-ol(1257398-99-4)
• EPA Substance Registry System: (2S,3R,4R)-4-(4-benzylpiperidin-1-yl)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)-5-methylenetetrahydrofuran-3-ol(1257398-99-4)

Safety Data

• Hazardous Substances Data: 1257398-99-4(Hazardous Substances Data)

Upstream product

• 31252-42-3 4-benzylpyperidine 
• 489459-65-6 (1S,2R,5S)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-methylene-3,6-dioxabicyclo[3.1.0]hexane 

Relevant articles and documents

1-exo-alkylidene-2,3-anhydrofuranoses: Valuable synthons in the preparation of furanose-based templates

Highly functionalized 1-exo-alkylidene-2,3-anhydro-, and 1′-halo-1-exo-alkylidene-2,3-anhydrofuranoses can be prepared in four or five steps, respectively, from D-mannose. These compounds feature a variety of functionalities, including a double bond, an oxirane, an allylic oxirane and (in the case of the 1′-halo derivative) an alkenyl halide. The reactivity of each functionality in these derivatives has been explored, and the usefulness of these substrates has been demonstrated with the preparation of furanose-based carbohydrate templates with up to four sites of molecular diversity. A highly functionalized 1-exo-alkylidene-2,3-anhydro-furanose, available in four steps from D-mannose, is a useful substrate that can be transformed into a variety of furanose derivatives including compounds with up to four sites for diversity.