125741-54-0

Basic information

• Product Name: (E)-N'-(2-hydroxybenzylidene)-4-methoxybenzohydrazide
• Synonyms: (E)-N'-(2-hydroxybenzylidene)-4-methoxybenzohydrazide
• CAS NO: 125741-54-0
• Molecular Weight: 270.288
• Mol File: 125741-54-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (E)-N'-(2-hydroxybenzylidene)-4-methoxybenzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N'-(2-hydroxybenzylidene)-4-methoxybenzohydrazide(125741-54-0)
• EPA Substance Registry System: (E)-N'-(2-hydroxybenzylidene)-4-methoxybenzohydrazide(125741-54-0)

Safety Data

• Hazardous Substances Data: 125741-54-0(Hazardous Substances Data)

Upstream product

• 121-98-2 methyl 4-methoxybenzoate 
• 89-95-2 2-methyl-benzyl alcohol 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 90-02-8 salicylaldehyde 

Downstream Products

• 23864-91-7 2-(4-methoxybenzoyl)benzaldehyde 

Relevant articles and documents

METHOD FOR PREPAREING 1,3,4-OXADIAZOL UNDER SOLVENT-FREE CONDITION

The present invention relates to a synthesis method of 1,3,4-oxadiazol, comprising: 1) under a solvent-free condition and by means of a mechanical pulverization method, making a hydrazide compound react with an aldehyde compound and thereby synthesizing a N-acylhydrazone compound; and 2) under a solvent-free condition, adding an iodine-based oxidizing agent to the N-acylhydrazone compound to synthesize 1,3,4-oxadiazol via oxidative cyclization. The solventless synthesis method of 1,3,4-oxadiazol according to the present invention is easy to perform and handle, and has the advantage of synthesizing 1,3,4-oxadiazol at high selectivity and yield. Also, the solventless synthesis method of the present invention can prevent the formation of side products caused by the minute amount of water that usually remains in solvents, and can further prevent synthesized intermediates from being converted back into the starting materials by the water.COPYRIGHT KIPO 2016

Phthalides by rhodium-catalyzed ketone hydroacylation

(Chemical Equation Presented) Phthalides are biologically relevant five-membered lactones found in herbs, fruits, and vegetables. Herein we communicate the first atom-economical approach to phthalides by using enantioselective ketone hydroacylation. In the presence of Rh[(Duanphos)]X (X = NO3, OTf, OMs), various 2-ketobenzaldehydes undergo intramolecular hydroacylation to produce phthalide products in good yields and 92-98% ee's. Our study highlights the key role counterions play in controlling both reactivity and enantioselectivity. A concise asymmetric total synthesis of the celery extract (S)-(-)-3-n-butylphthalide is also presented.

Synthesis and characterization of iron(III) complexes of salicylaldehyde 4-methoxybenzoyl hydrazone

Iron(III) complexes of salicylaldehyde 4-methoxybenzoyl hydrazone, (H2smbhon), have been isolated and the reactions of [Fe(smbhon) (Cl) (H2O)]2 with SnCl2 and CH3CN are discussed. These complexes have