1257554-80-5 Usage
General Description
2H-Pyrrolo[2,3-b]pyridin-2-one, 1,3-dihydro-1,3,3-trimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, also known as JQ1, is a potent and selective small molecule inhibitor of the bromodomain and extra-terminal (BET) proteins. It has been extensively studied for its anti-cancer properties, particularly in the treatment of various types of solid tumors and hematological malignancies. JQ1 works by binding to the acetyl-lysine recognition motifs present in the bromodomains of BET proteins, leading to suppression of oncogenic transcriptional programs and inhibition of tumor growth. Its unique chemical structure and mechanism of action make it a promising candidate for the development of novel targeted cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1257554-80-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,7,5,5 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1257554-80:
(9*1)+(8*2)+(7*5)+(6*7)+(5*5)+(4*5)+(3*4)+(2*8)+(1*0)=175
175 % 10 = 5
So 1257554-80-5 is a valid CAS Registry Number.