1257585-32-2

Upstream product

• 137364-87-5 4-(aminomethyl)-N-(2-hydroxyethyl)benzamide hydrochloride 
• 133380-41-3 methyl 5-(chlorocarbonyl)thiophene-2-carboxylate 
• 96736-02-6 tert-butyl 4-(2-hydroxyethylcarbamoyl)benzylcarbamate 
• 1257585-84-4 potassium 5-(methoxycarbonyl)-thiophene-2-carboxylate 
• 159691-07-3 N-(hydroxyethyl)-4-(aminomethyl)benzamide 
• 4282-34-2 Dimethyl thiophene-2,5-dicarboxylate 
• 33233-67-9 4-(tert-Butoxycarbonylaminomethyl)benzoic acid 
• 56-91-7 p-aminomethylbenzoic acid 

Downstream Products

• 1257585-33-3 5-(hydrazinecarbonyl)-N-[4-(2-hydroxyethylcarbamoyl)benzyl]thiophene-2-carboxamide 

Relevant academic research and scientific papers

FUSED HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS

Fused heterocyclic compounds useful for prevention, treatment or improvement of diseases against which activation of the thrombopoietin receptor is effective are provided. A compound represented by the formula (I) (wherein R1 is an aryl group fused to a saturated ring or the like, A, B, L1, R2, L2, L3, Y, L4, R3 and X are defined in the description), a tautomer, prodrug or a pharmaceutically acceptable salt of the compound or a solvate thereof.

HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER

An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various disorders is provided. An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells containing a compound represented by the formula (I) (wherein X, Y, Z, Ar1, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof, which can expand hematopoietic stem cells and/or hematopoietic progenitor cells.