125781-60-4 Usage
Uses
Used in Pharmaceutical Industry:
(S)-3-Hydroxymandelonitrile is used as a key component in the development of pharmaceutical treatments for various conditions, such as cancer, hypertension, and certain eye disorders. Its potential therapeutic applications are attributed to its complex structure and the presence of functional groups that can interact with biological targets.
Used in Cancer Treatment:
In the field of oncology, (S)-3-Hydroxymandelonitrile is employed as a potential anticancer agent. Its complex structure allows it to interact with cellular targets, inhibiting the growth and proliferation of cancer cells. (S)-3-HYDROXYMANDELONITRILE's ability to modulate signaling pathways and disrupt cellular processes makes it a promising candidate for the development of novel cancer therapies.
Used in Hypertension Management:
(S)-3-Hydroxymandelonitrile is also used in the management of hypertension, a condition characterized by high blood pressure. Its potential role in this context is linked to its ability to influence vascular function and blood pressure regulation, offering a new avenue for the development of antihypertensive drugs.
Used in Ophthalmology:
In the field of ophthalmology, (S)-3-Hydroxymandelonitrile is utilized for the treatment of certain eye conditions. Its potential applications in this area are related to its ability to modulate ocular processes and protect against damage, making it a valuable compound for the development of new ophthalmic treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 125781-60-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,7,8 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 125781-60:
(8*1)+(7*2)+(6*5)+(5*7)+(4*8)+(3*1)+(2*6)+(1*0)=134
134 % 10 = 4
So 125781-60-4 is a valid CAS Registry Number.
125781-60-4Relevant articles and documents
ENZYME-CATALYZED SYNTHESIS OF (S)-CYANOHYDRINS AND SUBSEQUENT HYDROLYSIS TO (S)-α-HYDROXY-CARBOXYLIC ACIDS
Effenberger, Franz,Hoersch, Brigitte,Foerster, Siegfried,Ziegler, Thomas
, p. 1249 - 1252 (2007/10/02)
(S)-Cyanohydrins 2 are obtained with high enantioselectivity from aromatic aldehydes and HCN in the presence of (S)-oxynitrilase (E.C.4.1.2.11).Acid-catalyzed hydrolysis of the cyanohydrins 2 affords the corresponding (S)-α-hydroxy carboxylic acids 3 without racemization.
Asymmetric Hydrocyanation of a Range of Aromatic and Aliphatic Aldehydes
Matthews, Barry R.,Jackson, W. Roy,Jayatilake, Gamini S.,Wilshire, Colin,Jacobs, Howard A.
, p. 1697 - 1710 (2007/10/02)
A range of aryl, alkyl and heterocyclic aldehydes have been treated with hydrogen cyanide in the presence of the 'Inoue' catalyst, (R,R)- or (S,S)-cyclo.Most aryl aldehydes with electron-donating substituents in the m-or p-positions give high enantiomeric excess (e.e) values (>=80percent) but aryl aldehydes with strong electron-withdrawing substituents gave moderate e.e. values (=50percent).These moderate values are believed to be due to partial racemization of the product cyanohydrins in the presence of the mildly basic catalyst.In contrast to the reactions of aryl aldehydes, reactions of alkyl aldehydes and of ketones gave low e.e. values (=30percent) and an explanation is proposed.
