125782-33-4Relevant academic research and scientific papers
Catalytic enantioselective synthesis of vicinal dialkyl arrays
Van Zijl, Anthoni W.,Szymanski, Wiktor,Lopez, Ferrnando,Minnaard, Adriaan J.,Feringa, Ben L.
supporting information; experimental part, p. 6994 - 7002 (2009/05/09)
(Chemical Equation Presented) With a consecutive "asymmetric allylic alkylation (AAA)/cross-metathesis (CM)/conjugate addition (CA)" protocol it is possible to synthesize either stereoisomer of compounds containing a vicinal dialkyl array with excellent stereoselectivity. The versatility of this protocol in natural product synthesis is demonstrated in the preparation of the ant pheromones faranal and lasiol.
Synthesis, conformation, and immunosuppressive activity of cyclosporines that contain ε-oxygen (4R)-4-[(E)-butenyl]-4,N-dimethyl-L-threonine analogues in the 1-position
Sun,Guillaume,Dunlap,Rich
, p. 1443 - 1452 (2007/10/02)
A series of CsA analogues that contain novel ε-oxygen isosteres of (4R)-4-[(E)-butenyl]-4,N-dimethyl-L-threonine (MeBmt) in the 1-position were synthesized. The key steps for the syntheses of enantiomerically pure ε-oxygen MeBmt analogues 4-7 were based o
