125785-69-5

Basic information

• Product Name: N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium
• Synonyms: N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium;Haloperidol pyridiniuM Chloride
• CAS NO: 125785-69-5
• Molecular Formula: C21H18 Cl F N O
• Molecular Weight: 354.8246
• Mol File: 125785-69-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium(125785-69-5)
• EPA Substance Registry System: N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium(125785-69-5)

Safety Data

• Hazardous Substances Data: 125785-69-5(Hazardous Substances Data)

Usage

Description

N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium is a pyridinium-based compound that is a metabolite of haloperidol, a commonly used antipsychotic drug. It is formed in the liver and can be found in the brain. N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium has neurotoxic properties and is a substrate for human organic cation transporters, which play a role in its transport and distribution within the body.

Uses

Used in Pharmaceutical Industry:
N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium is used as a research compound for studying the metabolism and toxic effects of haloperidol. Understanding its role in the body can help in the development of safer and more effective antipsychotic medications.
Used in Neuropharmacology Research:
As a neurotoxic pyridinium metabolite, N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium is utilized in neuropharmacological research to investigate the mechanisms of action and potential side effects associated with haloperidol use. This can contribute to a better understanding of the drug's impact on the central nervous system and inform the development of alternative treatments with fewer side effects.
Used in Drug Transport Studies:
N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium serves as a valuable tool in studying the function and regulation of human organic cation transporters. These transporters are crucial for the absorption, distribution, and elimination of various drugs, and understanding their role can help optimize drug delivery and reduce the risk of adverse effects.