125786-79-0Relevant academic research and scientific papers
STUDIES ON THE SYNTHESIS OF NUCLEOTIDYL-PEPTIDE. I: A FACILE SYNTHESIS INVOLVING SELECTIVE P-S BOND CLEAVAGE
Hotoda, Hitoshi,Ueno, Yoshihito,Sekine, Mitsuo,Hata, Tsujiaki
, p. 2117 - 2120 (2007/10/02)
A dinucleotide dipeptide (H-Ala-Tyr-(pUpU)-OH) was synthesized via a phosphorothioate triester intermediate (1).It was found that the P-S bond was selectively cleaved by the use of (n-Bu3Sn)2O without undesired dephosphorylation of tyrosine.
