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CAS

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1257881-62-1

2-[3-(4-chloro-phenoxy)-benzyl]-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid pyridin-3-ylamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1257881-62-1 Structure

  • Basic information

    1. Product Name: 2-[3-(4-chloro-phenoxy)-benzyl]-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid pyridin-3-ylamide
    2. Synonyms:
    3. CAS NO:1257881-62-1
    4. Molecular Formula:
    5. Molecular Weight: 462.979
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1257881-62-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-[3-(4-chloro-phenoxy)-benzyl]-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid pyridin-3-ylamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-[3-(4-chloro-phenoxy)-benzyl]-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid pyridin-3-ylamide(1257881-62-1)
    11. EPA Substance Registry System: 2-[3-(4-chloro-phenoxy)-benzyl]-2,7-diaza-spiro[3.5]nonane-7-carboxylic acid pyridin-3-ylamide(1257881-62-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1257881-62-1(Hazardous Substances Data)

1257881-62-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1257881-62-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,7,8,8 and 1 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1257881-62:
(9*1)+(8*2)+(7*5)+(6*7)+(5*8)+(4*8)+(3*1)+(2*6)+(1*2)=191
191 % 10 = 1
So 1257881-62-1 is a valid CAS Registry Number.

1257881-62-1Downstream Products

1257881-62-1Relevant articles and documents

Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase

Keith, John M.,Jones, William M.,Pierce, Joan M.,Seierstad, Mark,Palmer, James A.,Webb, Michael,Karbarz, Mark J.,Scott, Brian P.,Wilson, Sandy J.,Luo, Lin,Wennerholm, Michelle L.,Chang, Leon,Brown, Sean M.,Rizzolio, Michele,Rynberg, Raymond,Chaplan, Sandra R.,Breitenbucher, J. Guy

, p. 737 - 741 (2014/02/14)

A series of mechanism based heteroaryl urea fatty acid amide hydrolase (FAAH) inhibitors with spirocyclic diamine cores is described. A potent member of this class, (37), was found to inhibit FAAH centrally, elevate the brain levels of three fatty acid ethanolamides [FAAs: anandamide (AEA), oleoyl ethanolamide (OEA) and palmitoyl ethanolamide (PEA)], and was moderately efficacious in a rat model of neuropathic pain.

HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE

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Page/Page column 42-43, (2010/12/29)

Certain heteroaryl-substituted spirocyclic diamine urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis).

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