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1257882-85-1

7-(3-(4-chlorophenoxy)benzyl)-N-(4-(trifluoromethyl)pyridin-3-yl)-2,7-diazaspiro[3.5]nonane-2-carboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 7-(3-(4-chlorophenoxy)benzyl)-N-(4-(trifluoromethyl)pyridin-3-yl)-2,7-diazaspiro[3.5]nonane-2-carboxamide

    Cas No: 1257882-85-1

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  • 1257882-85-1 Structure

  • Basic information

    1. Product Name: 7-(3-(4-chlorophenoxy)benzyl)-N-(4-(trifluoromethyl)pyridin-3-yl)-2,7-diazaspiro[3.5]nonane-2-carboxamide
    2. Synonyms:
    3. CAS NO:1257882-85-1
    4. Molecular Formula:
    5. Molecular Weight: 530.977
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1257882-85-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-(3-(4-chlorophenoxy)benzyl)-N-(4-(trifluoromethyl)pyridin-3-yl)-2,7-diazaspiro[3.5]nonane-2-carboxamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-(3-(4-chlorophenoxy)benzyl)-N-(4-(trifluoromethyl)pyridin-3-yl)-2,7-diazaspiro[3.5]nonane-2-carboxamide(1257882-85-1)
    11. EPA Substance Registry System: 7-(3-(4-chlorophenoxy)benzyl)-N-(4-(trifluoromethyl)pyridin-3-yl)-2,7-diazaspiro[3.5]nonane-2-carboxamide(1257882-85-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1257882-85-1(Hazardous Substances Data)

1257882-85-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1257882-85-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,7,8,8 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1257882-85:
(9*1)+(8*2)+(7*5)+(6*7)+(5*8)+(4*8)+(3*2)+(2*8)+(1*5)=201
201 % 10 = 1
So 1257882-85-1 is a valid CAS Registry Number.

1257882-85-1Downstream Products

1257882-85-1Relevant articles and documents

Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase

Keith, John M.,Jones, William M.,Pierce, Joan M.,Seierstad, Mark,Palmer, James A.,Webb, Michael,Karbarz, Mark J.,Scott, Brian P.,Wilson, Sandy J.,Luo, Lin,Wennerholm, Michelle L.,Chang, Leon,Brown, Sean M.,Rizzolio, Michele,Rynberg, Raymond,Chaplan, Sandra R.,Breitenbucher, J. Guy

, p. 737 - 741 (2014/02/14)

A series of mechanism based heteroaryl urea fatty acid amide hydrolase (FAAH) inhibitors with spirocyclic diamine cores is described. A potent member of this class, (37), was found to inhibit FAAH centrally, elevate the brain levels of three fatty acid ethanolamides [FAAs: anandamide (AEA), oleoyl ethanolamide (OEA) and palmitoyl ethanolamide (PEA)], and was moderately efficacious in a rat model of neuropathic pain.

HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE

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Page/Page column 71, (2010/12/29)

Certain heteroaryl-substituted spirocyclic diamine urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis).

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