1258005-79-6Relevant academic research and scientific papers
Synthesis of L-iduronic acid derivatives via [3.2.1] and [2.2.2] L-iduronic lactones from bulk glucose-derived cyanohydrin hydrolysis: A reversible conformationally switched superdisarmed/rearmed lactone route to heparin disaccharides
Hansen, Steen U.,Dalton, Charlotte E.,Baráth, Marek,Kwan, Glenn,Raftery, James,Jayson, Gordon C.,Miller, Gavin J.,Gardiner, John M.
, p. 3777 - 3789 (2015)
l-Idofuranoside cyanohydrin 1 is converted on large scale into a mixture of l-IdoA methyl pyranosides and furanosides, which is converged to provide short 2-step routes to bicyclic [3.2.1] or [2.2.2] l-iduronate lactones. The former is obtained via a 100
