1258013-25-0

Basic information

• Product Name: N-(4-cyano-3-(trifluoromethyl)phenyl)-2-(6-(piperazin-1-yl)pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide
• Synonyms: N-(4-cyano-3-(trifluoromethyl)phenyl)-2-(6-(piperazin-1-yl)pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide
• CAS NO: 1258013-25-0
• Molecular Weight: 491.475
• Mol File: 1258013-25-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-cyano-3-(trifluoromethyl)phenyl)-2-(6-(piperazin-1-yl)pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-cyano-3-(trifluoromethyl)phenyl)-2-(6-(piperazin-1-yl)pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide(1258013-25-0)
• EPA Substance Registry System: N-(4-cyano-3-(trifluoromethyl)phenyl)-2-(6-(piperazin-1-yl)pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide(1258013-25-0)

Safety Data

• Hazardous Substances Data: 1258013-25-0(Hazardous Substances Data)

Upstream product

• 1344033-99-3 tert-butyl 4-(5-(4-(4-cyano-3-(trifluoromethyl)phenylcarbamoyl)-1H-benzo[d]imidazol-2-yl)pyridin-2-yl)piperazine-1-carboxylate 
• 1344033-98-2 2-(6-chloropyridin-3-yl)-N-(4-cyano-3-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole-4-carboxamide 
• 654-70-6 4-amino-2-trifluoromethylbenzonitrile 
• 330948-01-1 2-(6-chloropyridin-3-yl)-1H-benzo[d]imidazole-4-carboxylic acid 

Relevant articles and documents

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Provided are methods and compositions for detecting a compound that activates a sirtuin deacetylase activity on a fluorescent-free activation substrate in vitro. Further provided are sirtuin modulating compounds of the formulas (I)-(XXI), and related compounds (XXXI), (XXXII), (XXXIII), and (XXXIV), including the fluorescent free-substrate SIRT1 activator compounds of formulas (XL), (XI), (XII), and (XIII).