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Unexpected Formation of Nitriles from Reactions of 6-(Dibromomethyl)-1,2,3,4-tetrahydro-2-oxo-5-pyrimidinearboxylates with Sodium Azide
Kappe, Oliver C.
, p. 505 - 507 (2007/10/02)
The action of sodium azide on (dibromomethyl)pyrimidines 2a and 8a leads to the nitriles 3a and 9, whereas the 1-methyl derivatives 2b and 8b afford the geminal diazides 7 and 10.The nitriles 3a,b add another mole of azide to give the tetrazoles 4a, b.The
