1258203-98-3Relevant academic research and scientific papers
An asymmetric iodolactonization reaction catalyzed by a zinc bis-proline-phenol complex
Filippova, Liudmila,Stenstr?m, Yngve,Hansen, Trond Vidar
supporting information, p. 419 - 422 (2014/01/06)
The intramolecular zinc bis-proline-phenol complex 2a was found to promote enantioselective iodolactonization reactions of both electron-rich and electron-poor 5-aryl-5-hexenoic acids affording δ-iodolactones in good chemical yields with up to 82% enantio
Asymmetric iodolactonization utilizing chiral squaramides
Tungen, Jorn E.,Nolsoe, Jens M. J.,Hansen, Trond V.
, p. 5884 - 5887 (2013/02/23)
Asymmetric iodolactonization of γ- and δ-unsaturated carboxylic acids has been explored in the presence of six different chiral organocatalysts 5-8. The catalyst 6b was found to facilitate the cyclization of 5-arylhex-5-enoic acids 1 to the corresponding
Tertiary aminourea-catalyzed enantioselective iodolactonization
Veitch, Gemma E.,Jacobsen, Eric N.
supporting information; experimental part, p. 7332 - 7335 (2010/12/18)
Binding the anion : A highly enantioselective iodolactonization of 5-hexenoic acids has been achieved using a tertiary aminourea-catalyst (see scheme). The use of catalytic iodine in this process is critical to enhancing both the reactivity and enantioselectivity of the stoichiometric I+ source. The mechanism is proposed to involve binding of an iodonium imidate intermediate by the H-bond donor catalyst.
