1258204-09-9Relevant articles and documents
Tertiary aminourea-catalyzed enantioselective iodolactonization
Veitch, Gemma E.,Jacobsen, Eric N.
, p. 7332 - 7335 (2010)
Binding the anion : A highly enantioselective iodolactonization of 5-hexenoic acids has been achieved using a tertiary aminourea-catalyst (see scheme). The use of catalytic iodine in this process is critical to enhancing both the reactivity and enantioselectivity of the stoichiometric I+ source. The mechanism is proposed to involve binding of an iodonium imidate intermediate by the H-bond donor catalyst.