1258268-37-9

Basic information

• Product Name: C₂₄H₁₉ClN₆
• CAS NO: 1258268-37-9
• Molecular Weight: 426.908
• Mol File: 1258268-37-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₁₉ClN₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₁₉ClN₆(1258268-37-9)
• EPA Substance Registry System: C₂₄H₁₉ClN₆(1258268-37-9)

Safety Data

• Hazardous Substances Data: 1258268-37-9(Hazardous Substances Data)

Upstream product

• 107918-32-1 N-(biphenyl-2-yl)-4,6-dichloro-1,3,5-triazin-2-amine 
• 3468-17-5 1-(1H-indol-6-yl)methanamine 

Downstream Products

• 1258268-14-2 C₂₄H₂₀N₆O 

Relevant articles and documents

Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1

The discovery and SAR study of a series of 4,6-diamino-1,3,5-triazin-2-ol compounds as novel HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are reported. The lead compounds in this series showed excellent activity against wild-type and drug-resistant RT enzymes and viral strains. In addition, compounds from this series demonstrated favorable pharmacokinetic profile in rat. A preliminary modeling study was conducted to understand the binding mode of this series of compounds.