125827-01-2

Basic information

• Product Name: 3^A-amino-3^A-deoxy-β-cyclodextrin
• Synonyms: 3^A-amino-3^A-deoxy-β-cyclodextrin
• CAS NO: 125827-01-2
• Molecular Weight: 1134.01
• Mol File: 125827-01-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3^A-amino-3^A-deoxy-β-cyclodextrin(CAS DataBase Reference)
• NIST Chemistry Reference: 3^A-amino-3^A-deoxy-β-cyclodextrin(125827-01-2)
• EPA Substance Registry System: 3^A-amino-3^A-deoxy-β-cyclodextrin(125827-01-2)

Safety Data

• Hazardous Substances Data: 125827-01-2(Hazardous Substances Data)

Upstream product

• 161523-00-8 3^A-azido-3^A-deoxy-altro-β-cyclodextrin 
• 84648-78-2 β-cyclodextrin-2,3-mannoepoxide 

Downstream Products

• 1515864-99-9 C₅₁H₇₇NO₃₇ 

Relevant articles and documents

Cyclodextrin retinylidene: A biomimetic kinetic trap model for rhodopsin

All trans retinal was attached to both the primary face and the secondary face of β-cyclodextrin via a Schiff base linkage, analogous to that in rhodopsin. The new models were evaluated and compared with n-butylamine retinylidene Schiff base for their rates of hydrolysis, and factors that influence such rates. Competition studies using adamantane carboxylate demonstrated the kinetic trap theory by diminishing the binding of retinal in the cyclodextrin, thereby augmenting the rate of hydrolysis. NMR experiments indicate that the retinylidene is most probably bound in the form of a dimer.

Synthesis and Chiral Recognition Property of 3-Acetylamino-3-deoxy-β-cyclodextrin

Mono(3-acetylamino-3-deoxy)-β-cyclodextrin (4) was firstly prepared via regioselective ring opening of manno-epoxide by ammonia. 1H-NMR investigation clearly demonstrated that 4 recognized the chirality of mandelic acids and N-acetyl-phenyl-glycine by the formation of diastereomeric inclusion complexes.