1258271-18-9Relevant academic research and scientific papers
2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase
Lee, Hsueh-Yun,Chang, Chih-Yi,Su, Chih-Jou,Huang, Han-Li,Mehndiratta, Samir,Chao, Yuh-Hsuan,Hsu, Chia-Ming,Kumar, Sunil,Sung, Ting-Yi,Huang, Yi-Zhen,Li, Yu-Hsuan,Yang, Chia-Ron,Liou, Jing-Ping
, p. 92 - 101 (2016)
This study reports the design and synthesis of 2-(phenylsulfonyl)quinoline N-hydroxyacrylamides (8a–k). Structure-activity relationship studies focusing on regio-effect of N-hydroxyacrylamide moiety and influence of the sulfonyl linker revealed that N-hyd
