1258271-56-5Relevant academic research and scientific papers
An easy synthetic approach to 1,2,3-triazole-fused heterocycles
Fiandanese, Vito,Marchese, Giuseppe,Punzi, Angela,Iannone, Francesco,Rafaschieri, Giacomo G.
experimental part, p. 8846 - 8853 (2010/11/19)
A convenient synthesis of 1,2,3-triazole-fused isoindolines and dihydroisoquinolines in good to excellent yield is reported, starting from easily available terminal alkynes and (2-haloaryl)alkylazides. The method is based upon a cycloaddition reaction, via click chemistry, followed by a transition metal-catalyzed functionalization of a C-H bond.
