1258271-61-2

Upstream product

• 1258271-45-2 1-(2-bromobenzyl)-4-(4-methylphenyl)-1H-1,2,3-triazole 
• 1235527-70-4 1-(2-iodobenzyl)-4-(p-tolyl)-1H-1,2,3-triazole 
• 1138734-88-9 1-(azidomethyl)-2-(p-tolylethynyl)benzene 
• 40400-13-3 2-Iodobenzyl bromide 
• 766-97-2 4-n-methylphenylacetylene 

Relevant academic research and scientific papers

Selectfluor-mediated synthesis of isoindoline fused with triazoles under metal-free conditions

An efficient selectfluor-mediated cyclisation of 2-arylethynyl-benzyl azides at 80 °C in MeCN yielded 12 arylated triazolo-isoindoline derivatives (seven of which are novel). Products bearing either electron-donating or electron-withdrawing groups on the

A continuous flow approach for the C-H functionalization of 1,2,3-triazoles in γ-valerolactone as a biomass-derived medium

Herein we report an efficient procedure for the C-H functionalization of 1,2,3-triazoles in a continuous flow regime applied to a variety of functionalities and to the inter- or intramolecular versions of the process. The continuous-flow protocol is based

Bifunctional metal organic framework catalysts for multistep reactions: MOF-Cu(BTC)-[Pd] catalyst for one-pot heteroannulation of acetylenic compounds

A bifunctional metal organic framework catalyst containing palladium and copper(II) benzene-1,3,5-tricarboxylate - MOF-Cu(BTC)-[Pd] - has been prepared. This catalyst enables the performance of the tandem Sonogashira/click reaction starting from 2-iodoben

An easy synthetic approach to 1,2,3-triazole-fused heterocycles

A convenient synthesis of 1,2,3-triazole-fused isoindolines and dihydroisoquinolines in good to excellent yield is reported, starting from easily available terminal alkynes and (2-haloaryl)alkylazides. The method is based upon a cycloaddition reaction, via click chemistry, followed by a transition metal-catalyzed functionalization of a C-H bond.