1258271-62-3Relevant academic research and scientific papers
Palladium and copper-supported on charcoal: A heterogeneous multi-task catalyst for sequential Sonogashira-Click and Click-Heck reactions
Rossy, Cybille,Majimel, Jér?me,Delapierre, Mona Tréguer,Fouquet, Eric,Felpin, Fran?ois-Xavier
, p. 78 - 85 (2014)
This paper describes the development of one-pot sequential Sonogashira-Click and Click-Heck reactions by using Pd-Cu/C as a heterogeneous multi-task catalyst for the synthesis of heterocyclic structures. Details of the optimization studies and the substrate scope are discussed. These methodologies allow the preparation of functionalized triazoles in simple experimental conditions with inexpensive reagents.
Facile synthesis of [1,2,3]-triazole-fused isoindolines, tetrahydroisoquinolines, benzoazepines and benzoazocines by palladium-copper catalysed heterocyclisation
Brahma, Kaushik,Achari, Basudeb,Chowdhury, Chinmay
, p. 545 - 555 (2013/04/10)
An elegant method for the synthesis of 1,2,3-triazoles fused with five-, six-, seven- and eight-membered benzoheterocycles, including isoindoline, tetrahydroisoquinoline, benzoazepine and benzoazocine, has been developed via palladium-copper catalysed reactions in one-pot. The broad scope of this reaction was illustrated by effecting bis-heteroannulations, synthesis of uracil derivatives of biological interest, and employment of acetylene gas as an inexpensive substrate. The reactions are experimentally simple and utilise easily accessible substrates of different types. Georg Thieme Verlag Stuttgart · New York.
Bifunctional metal organic framework catalysts for multistep reactions: MOF-Cu(BTC)-[Pd] catalyst for one-pot heteroannulation of acetylenic compounds
Arnanz, Avelina,Pintado-Sierra, Mercedes,Corma, Avelino,Iglesias, Marta,Sanchez, Felix
experimental part, p. 1347 - 1355 (2012/06/30)
A bifunctional metal organic framework catalyst containing palladium and copper(II) benzene-1,3,5-tricarboxylate - MOF-Cu(BTC)-[Pd] - has been prepared. This catalyst enables the performance of the tandem Sonogashira/click reaction starting from 2-iodoben
An easy synthetic approach to 1,2,3-triazole-fused heterocycles
Fiandanese, Vito,Marchese, Giuseppe,Punzi, Angela,Iannone, Francesco,Rafaschieri, Giacomo G.
experimental part, p. 8846 - 8853 (2010/11/19)
A convenient synthesis of 1,2,3-triazole-fused isoindolines and dihydroisoquinolines in good to excellent yield is reported, starting from easily available terminal alkynes and (2-haloaryl)alkylazides. The method is based upon a cycloaddition reaction, via click chemistry, followed by a transition metal-catalyzed functionalization of a C-H bond.
