1258282-20-0Relevant academic research and scientific papers
Concise synthesis and antiangiogenic activity of artemisinin-glycolipid hybrids on chorioallantoic membranes
Ricci, Jérémy,Park, Jeehyun,Chung, Won-Yoon,Park, Kwang-Kyun,Jung, Mankil
, p. 6858 - 6860 (2010)
Novel hybrids of non acetal and acetal-type derivatives at C-12 of artemisinin and glycolipids were synthesized via efficient coupling reactions. Some of these hybrids showed potent in vivo antiangiogenic activity on the chorioallantoic membrane (CAM) that was higher than or comparable to those of fumagillin and thalidomide at a concentration of 2.5 nmol.
