1258312-86-5Relevant articles and documents
Pd(II)-catalyzed annulation of N-benzyl-N-aroylmethyl-2-alkynamides with arylboronic acids: An efficient synthesis of highly substituted α-alkylidene-β-hydroxy-γ-lactams
Wang, Huan,Han, Xiuling,Lu, Xiyan
supporting information; experimental part, p. 9129 - 9134 (2011/01/12)
A simple palladium(II)-catalyzed intramolecular addition of vinylpalladium species to ketones initiated by the carbopalladation of alkynamides under mild conditions without a Pd(II)/Pd(0) redox system was developed. This cascade reaction provides a new approach for the synthesis of highly substituted α-alkylidene-β-hydroxy-γ-lactams.