Alpha-cobratoxin from Naja atra, also known as the Chinese cobra, is a highly potent neurotoxin found in the venom of this snake species. It is a specific antagonist of nicotinic acetylcholine receptors, which are essential for nerve impulse transmission. The neurotoxin's ability to bind to these receptors and inhibit nerve impulse transmission is the key to its paralyzing and immobilizing effects on prey. Alpha-cobratoxin's unique properties and mechanism of action make it a valuable tool for understanding the nervous system and exploring potential therapeutic applications in muscle disorders and neurological conditions.

12584-83-7

Post Buying Request

Basic information
1. Product Name: ALPHA-COBRATOXIN FROM NAJA ATRA
2. Synonyms: ALPHA-COBRATOXIN FROM NAJA ATRA;Cobrotoxin
3. CAS NO:12584-83-7
4. Molecular Formula: C277H443N97O98S8
5. Molecular Weight: 6956.59242
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 12584-83-7.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: −20°C
8. Solubility: N/A
9. CAS DataBase Reference: ALPHA-COBRATOXIN FROM NAJA ATRA(CAS DataBase Reference)
10. NIST Chemistry Reference: ALPHA-COBRATOXIN FROM NAJA ATRA(12584-83-7)
11. EPA Substance Registry System: ALPHA-COBRATOXIN FROM NAJA ATRA(12584-83-7)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany: 3
5. RTECS: GG4220000
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 12584-83-7(Hazardous Substances Data)

Suppliers
Usage
Upstream product
Downstream Products

12584-83-7 Suppliers

Recommended suppliers

12584-83-7 Usage

Uses

Used in Pharmaceutical Research:
Alpha-cobratoxin from Naja atra is used as a research tool for studying the structure and function of nicotinic acetylcholine receptors. Its high specificity and potency in binding to these receptors make it an ideal candidate for investigating the molecular mechanisms underlying nerve impulse transmission and muscle activation.
Used in Neurological and Muscle Disorder Research:
Alpha-cobratoxin is employed as a therapeutic agent in the research of muscle disorders and neurological conditions. Its ability to inhibit nerve impulse transmission and induce muscle paralysis has potential applications in the treatment of conditions such as myasthenia gravis, a neuromuscular disorder characterized by muscle weakness and fatigue.
Used in Drug Development:
The unique properties of alpha-cobratoxin make it a valuable component in the development of new drugs targeting nicotinic acetylcholine receptors. Its potential therapeutic applications in muscle disorders and neurological conditions have led to ongoing research into the development of novel drugs that can modulate these receptors for the treatment of various diseases.
Used in Venom Antidotes:
Due to its role in the venom's paralyzing effects, alpha-cobratoxin is also used in the development of antidotes for snakebites, specifically those caused by the Chinese cobra. Understanding the mechanism of action of this neurotoxin can aid in the creation of effective treatments to counteract the venom's effects and save lives in cases of envenomation.

Check Digit Verification of cas no

The CAS Registry Mumber 12584-83-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,5,8 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 12584-83:
(7*1)+(6*2)+(5*5)+(4*8)+(3*4)+(2*8)+(1*3)=107
107 % 10 = 7
So 12584-83-7 is a valid CAS Registry Number.

InChI:InChI=1/C277H443N97O98S8/c1-17-121(7)207(261(461)339-156(62-69-203(411)412)235(435)364-208(122(8)18-2)262(462)349-165(90-190(288)395)244(444)360-179(114-478)255(455)361-180(115-479)256(456)367-213(127(13)383)266(466)370-212(126(12)382)265(465)351-168(94-205(415)416)246(446)333-148(44-31-77-309-276(299)300)228(428)357-177(112-476)254(454)347-164(89-189(287)394)243(443)352-169(271(471)472)92-192(290)397)362-199(404)104-316-220(420)162(87-187(285)392)345-225(425)145(39-23-26-72-280)338-260(460)206(120(5)6)363-250(450)173(108-378)356-257(457)182-46-33-79-373(182)269(469)181(116-480)325-198(403)102-317-222(422)174(109-473)323-196(401)101-315-218(418)141(40-27-73-305-272(291)292)327-230(430)155(61-68-202(409)410)340-263(463)210(124(10)380)365-233(433)149(45-32-78-310-277(301)302)334-237(437)157(82-131-48-52-136(387)53-49-131)322-195(400)100-314-219(419)142(41-28-74-306-273(293)294)328-240(440)160(85-134-96-303-117-319-134)343-247(447)167(93-204(413)414)348-227(427)147(43-30-76-308-275(297)298)332-239(439)159(84-133

12584-83-7Upstream product

12584-83-7Downstream Products

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 12584-83-7