1258406-75-5Relevant academic research and scientific papers
Formal [3+2]-cycloaddition of ketenes and oxaziridines catalyzed by chiral lewis bases: Enantioselective synthesis of oxazolin-4-ones
Shao, Pan-Lin,Chen, Xiang-Yu,Ye, Song
supporting information; experimental part, p. 8412 - 8416 (2011/02/25)
Choose the right cat.: A highly enantioselective synthesis of oxazolin-4-ones by the formal [3+2]-cycloaddition of ketenes and a racemic oxaziridines has been developed (see scheme; cat.=N-heterocyclic carbenes for disubstituted ketenes or cinchona alkaloids for monosubstituted ketenes, Ts=4-toluenesulfonyl).
