1258407-26-9Relevant articles and documents
Simple preparation of N-protected chiral-amino alkyl thiols from corresponding iodides employing sodium trithiocarbonate
Madhu, Chilakapati,Hemantha, H. P.,Vishwanatha, T. M.,Sureshbabu, V. V.
, p. 228 - 235,8 (2020/09/02)
A simple protocol for the preparation of N-protected amino alkyl thiols is reported that employs a reaction of sodium trithiocarbonate (Na 2CS3) with N-protected amino alkyl iodides. Na 2CS3 is easy to prepare and the protocol circumvents the use of strong bases and multiple steps. All the thiol compounds made were obtained as enantiopure samples and were characterized employing NMR and mass spectrometry.
