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1258421-27-0

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1258421-27-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1258421-27-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,8,4,2 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1258421-27:
(9*1)+(8*2)+(7*5)+(6*8)+(5*4)+(4*2)+(3*1)+(2*2)+(1*7)=150
150 % 10 = 0
So 1258421-27-0 is a valid CAS Registry Number.

1258421-27-0Relevant articles and documents

2′ Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SAR

Budzik, Brian,Garzya, Vincenzo,Shi, Dongchuan,Foley, James J.,Rivero, Ralph A.,Langmead, Christopher J.,Watson, Jeannette,Wu, Zining,Forbes, Ian T.,Jin, Jian

supporting information; experimental part, p. 3540 - 3544 (2010/08/22)

Biaryl amides were discovered as novel and subtype selective M1 muscarinic acetylcholine receptor agonists. The identification, synthesis, and initial structure-activity relationships that led to compounds 3j and 4c, possessing good M1 agonist potency and intrinsic activity, and subtype selectivity for M1 over M2-5, are described.

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