1258442-37-3Relevant articles and documents
A practical solution-phase synthesis of an antagonistic peptide of TNF-α based on hydrophobic tag strategy
Tana, Gegen,Kitada, Shingo,Fujita, Shuji,Okada, Yohei,Kim, Shokaku,Chiba, Kazuhiro
supporting information; experimental part, p. 8219 - 8221 (2010/12/20)
A simple acid-resistant hydrophobic tag, which can be removed rapidly in a single-step procedure after overall peptide synthesis, has been developed to accomplish practical solution-phase synthesis of a 15-mer antagonistic peptide of TNF-α (A-TNF-α). Hydrophobically tagged peptides can be separated as precipitates at each step by addition of a polar organic solvent.