1258458-27-3Relevant articles and documents
Studies of anti-HIV transcription inhibitor quinolones: Identification of potent N1-vinyl derivatives
Tabarrini, Oriana,Massari, Serena,Daelemans, Dirk,Meschini, Francesco,Manfroni, Giuseppe,Bottega, Laura,Gatto, Barbara,Palumbo, Manlio,Pannecouque, Christophe,Cecchetti, Violetta
experimental part, p. 1880 - 1892 (2011/06/20)
The 6-desfluoroquinolones (6-DFQs) are anti-HIV agents that target Tat-mediated transcription. This particular mechanism of action makes this class of compounds very attractive for further structural investigations. Identification of the pharmacophore req