1258498-89-3Relevant academic research and scientific papers
The synthesis of aryl halomethylated unsaturated iminolactones
Zonouzi, Afsaneh,Rahmani, Hossein,Biniaz, Mojtaba,Izakian, Zakieh,Ng, Seik Weng
, p. 412 - 415 (2011)
Halomethylated iminolactones have been synthesised from alkyl isocyanides, acetylene dicarboxylic acid esters and halogenated acetophenones in solvent free microwave assisted multi-component reactions.
Three-component reaction of an isocyanide and a dialkyl acetylenedicarboxylate with a phenacyl halide in the presence of water: An efficient method for the one-pot synthesis of γ-iminolactone derivatives
Ramazani, Ali,Rezaei, Aram,Mahyari, Amir Tofangchi,Rouhani, Morteza,Khoobi, Mehdi
experimental part, p. 2033 - 2036 (2010/12/25)
The zwitterion, formed from the reaction of an alkyl isocyanide and a dialkyl acetylenedicarboxylate, reacts with phenacyl halides in H2O to produce γ-iminolactone derivatives in high yields. H2O helps to avoid the use of highly toxic and environmentally unfavorable solvents for this conversion.
