1258505-79-1Relevant articles and documents
Tetrapeptides, as small-sized peptidic inhibitors; synthesis and their inhibitory activity against BACE1
Kakizawa, Taeko,Hidaka, Koushi,Hamada, Daisuke,Yamaguchi, Ryoji,Uemura, Tsuyoshi,Kitamura, Hitomi,Tagad, Harichandra D.,Hamada, Takashi,Ziora, Zyta,Hamada, Yoshio,Kimura, Tooru,Kiso, Yoshiaki
, p. 257 - 262 (2011/03/18)
β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) is known to be involved in the production of amyloid β-peptide in Alzheimer's disease and is a major target for current drug design. We previously reported substrate-based peptidomimetics, KMI-com