1258512-43-4

Basic information

• Product Name: 2'-(4-chlorobenzoyl)-5,6'-difluoro-1,2'-spirobi[indene]-1,3-dione
• Synonyms: 2'-(4-chlorobenzoyl)-5,6'-difluoro-1,2'-spirobi[indene]-1,3-dione
• CAS NO: 1258512-43-4
• Molecular Weight: 420.799
• Mol File: 1258512-43-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2'-(4-chlorobenzoyl)-5,6'-difluoro-1,2'-spirobi[indene]-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-(4-chlorobenzoyl)-5,6'-difluoro-1,2'-spirobi[indene]-1,3-dione(1258512-43-4)
• EPA Substance Registry System: 2'-(4-chlorobenzoyl)-5,6'-difluoro-1,2'-spirobi[indene]-1,3-dione(1258512-43-4)

Safety Data

• Hazardous Substances Data: 1258512-43-4(Hazardous Substances Data)

Upstream product

• 89226-83-5 4-fluoro phthalaldehyde 
• 59142-68-6 2-bromo-4-fluorobenzaldehyde 
• 1258512-08-1 2-(1,3-dioxolan-2-yl)-5-fluorobenzaldehyde 
• 1258512-11-6 (E)-3-(2-(1,3-dioxolan-2-yl)-5-fluorophenyl)-1-(4-chlorophenyl)prop-2-en-1-one 
• 773097-04-4 2-(2-bromo-4-fluorophenyl)-1,3-dioxolane 
• 1258512-12-7 (E)-2-(3-(4-chlorophenyl)-3-oxoprop-1-enyl)-4-fluorobenzaldehyde 

Relevant articles and documents

Synthesis of spiro bis-indanes via domino Stetter-aldol-Michael and Stetter-aldol-aldol reactions: Scope and limitations

The synthesis of spiro bis-indanes by means of N-heterocyclic carbene (NHC) catalysis is reported. The dimerization of various o-formylchalcone substrates or their combination with phthaldialdehyde derivatives under the catalysis of thiazolium-derived carbenes afforded Stetter-aldol-Michael products and Stetter-aldol-aldol products, respectively. The use of poor Michael acceptors in conjunction with an N-alkyltriazolium-derived catalyst furnished a variety of dibenzo[8]annulene products. This work highlights the interplay of a variety of factors affecting competing pathways in NHC-catalyzed domino reactions. Georg Thieme Verlag Stuttgart - New York.