1258538-03-2Relevant academic research and scientific papers
Palladium-catalysed cyclisation of N-alkynyl aminomalonates
Hess, Wilfried,Burton, Jonathan W.
supporting information; experimental part, p. 12303 - 12306 (2011/02/23)
Go around in (hetero)cycles! The palladium-catalysed tandem cyclisation/coupling reaction of alkynyl- and alkenyl-substituted aminomalonates leads to highly functionalised pyrrolidines and piperidines in good yield (see scheme). The reaction allows efficient access to a broad range of synthetically valuable building blocks.
