1258619-23-6Relevant articles and documents
Palladium- and nickel-catalyzed direct alkylation of azoles with unactivated alkyl bromides and chlorides
Yao, Tomoyuki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
scheme or table, p. 12307 - 12311 (2011/02/16)
Long-ing alkyl chain: The catalytic direct C-H alkylation of azoles with unactivated alkyl bromides and chlorides is described. A palladium catalyst enables the alkylation of oxazoles, whereas a nickel one shows unique activity for thiazole. The catalyses allow a straightforward access to azole motifs bearing long, functional alkyl side chains.