125873-96-3

Upstream product

• 131466-89-2 (2S,4S)-2,4-Diisopropyl-1,5-dioxa-spiro[5.5]undecane 
• 18362-64-6 2,6-dimethyl-3,5-heptanedione 
• 108-94-1 cyclohexanone 
• 131466-89-2 (2R,4S)-2,4-Diisopropyl-1,5-dioxa-spiro[5.5]undecane 
• 65534-62-5 (3R^*,5S^*)-2,6-dimethyl-3,5-heptanediol 
• 125873-95-2 (3S,5S)-(-)-2,6-dimethyl-3,5-heptanediol 

Relevant academic research and scientific papers

DIASTEREO-DIFFERENTIATING CYCLOPROPANATION OF A CHIRAL ENOL ETHER: A SIMPLE METHOD FOR THE PREPARATION OF OPTICALLY PURE CYCLOPROPYL ETHERS

Enol ether of cyclohexanone carrying 2,4-pentanediol (PD) or 2,6-dimethyl-3,5-heptanediol (DMHD) as a chiral auxiliary was subjected to diastereo-differentiating cyclopropanation.The highest diastereomer excess (d.e.) of the product was found to be 95.2percent in the case of PD and over 99.5percent in the case of DMHD.The enol ethers prepared from various ketones and DMHD were also cyclopropanated in giving cyclopropyl ethers in almost 100percent d.e..

DIASTEREO-DIFFERENTIATING SIMMONS-SMITH REACTION USING A NEW CHIRAL AUXILIARY

Diastereo-differentiating Simmons-Smith reactions of enol ethers of various ketones were carried out by using (3S,5S)-2,6-dimethyl-3,5-heptanediol as a new chiral auxiliary.The diastereomer excess of these reactions reached to be >99 percent.