125877-13-6Relevant academic research and scientific papers
Three-Different-Component -Annulation Reactions: Ionic and Radical Cyclizations
Posner, Gary H.,Asirvatham, Edward,Hamill, Terence G.,Webb, Kevin S.
, p. 2132 - 2137 (2007/10/02)
One-carbon-atom Michael donors are used to initiate convergent and flexible -hexannulations and -pentannulations in which the initial nucleophilic carbon atom terminates the reaction sequence in an ionic fashion as an electrophilic center or in a carbon-centered radical fashion as a nucleophilic center.This protocol is used to prepare regiospecifically substituted bicyclic ketones and lactones and a cis-bicyclic tetrahydrofuran.
