125879-00-7

Upstream product

• 14318-66-2 3-methoxy-N-methylaniline 
• 23197-67-3 diethyl 2-(4-methoxyphenyl)malonate 

Downstream Products

• 125879-39-2 4,7-Diacetoxy-3-(4-acetoxyphenyl)-1-methyl-2(1H)-chinolon 
• 138617-04-6 7-methoxy-1-methyl-3-(4-methoxyphenyl)-4-(4-toluenesulfonyloxy)-2(1H)-quinolone 
• 138617-03-5 2,4-dichloro-7-methoxy-3-(4-methoxyphenyl)-quinoline 
• 138616-99-6 4-chloro-7-methoxy-1-methyl-3-(4-methoxyphenyl)-quinolin-2(1H)-one 
• 125879-11-0 (+/-)-3-Hydroxy-7-methoxy-3-(4-methoxyphenyl)-1-methyl-2,4(1H,3H)-chinolindion 
• 125879-35-8 4,7-Dihydroxy-3-(4-hydroxyphenyl)-1-methyl-2(1H)-chinolon 

Relevant academic research and scientific papers

Palladium-Catalyzed Ring Closure Reactions to Benzofuranes: A New and Effective Approach to Azacoumestrols

Azacoumestans (benzofuroquinolinones) 4 have been synthesized using the following three methods: ring closure of 3-aryl-4-hydroxy-2-quinolones 3a-e by Pd-catalyzed cyclodehydrogenation, ring closure of 3-hydroxy-3-aryl-2,4-quinolinediones 5 by acid-catalyzed cyclodehydratation, or ring closure of 4-aryloxy-3-iodo-quinolones 8, which are obtained by rearrangement of iodonium ylides 7, by palladium-mediated cyclodehydrohalogenation.Only the latter reaction yielded the coumestrol analog dimethoxy derivatives 4c, d, which have been transformed into the hydroxy and acetoxy derivatives 9, 10.