1258833-77-0

Basic information

• Product Name: 6-bromo-8-fluoroisoquinoline
• CAS NO: 1258833-77-0
• Molecular Weight: 226.048
• Mol File: 1258833-77-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 6-bromo-8-fluoroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-bromo-8-fluoroisoquinoline(1258833-77-0)
• EPA Substance Registry System: 6-bromo-8-fluoroisoquinoline(1258833-77-0)

Safety Data

• Hazardous Substances Data: 1258833-77-0(Hazardous Substances Data)

Usage

General Description

6-bromo-8-fluoroisoquinoline is a chemical compound with the molecular formula C9H5BrFN. It is classified as an isoquinoline derivative, containing a six-membered ring consisting of benzene and pyridine rings fused together. 6-bromo-8-fluoroisoquinoline is characterized by the presence of bromine and fluorine atoms, which impart unique chemical and physical properties. 6-bromo-8-fluoroisoquinoline has potential applications in the pharmaceutical and agrochemical industries, where its structural features may be utilized in the development of new drugs and pesticides. Additionally, it may also find use as a precursor in organic synthesis for the production of other valuable compounds. Understanding the properties and behavior of this chemical is important for researchers and industries seeking to harness its potential utility in various applications.

Upstream product

• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 1183945-15-4 N-(4-bromo-2-fluorobenzyl)-2,2-dimethoxyethan-1-amine 
• 1613147-80-0 N-(4-bromo-2-fluorobenzyl)-N-(2,2-dimethoxyethyl)benzenesulfonamide 
• 112734-22-2 4-bromo-2-fluorobenzylamine 

Downstream Products

• 1613147-83-3 (R)-5-(2-(tert-butoxycarbonyl)-8-fluoro-1,2,3,4-tetrahydroisoquinolin-6-yl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 
• 1613147-79-7 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(8-fluoro-1,2,3,4-tetrahydroisoquinolin-6-yl)pyridin-2-amine 

Relevant articles and documents

WDR5 INHIBITORS AND MODULATORS

Isoquinolmone compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.

TETRAHYDRO-BENZO[D]AZEPINE DERIVATIVES AS GPR120 MODULATORS

Novel tetrahydroisoquinoline and tetrahydrobenzazepine compounds of formula (I) capable of modulating the G-protein-coupled receptor GPR120, compositions comprising the compounds, and methods for their use for controlling insulin levelsin vivoand for the treatment of conditions such as of diabetes, inflammation, obesity and metabolic diseases. (I)

Substituted ring compound and its method and use thereof

The invention provides a substituted cyclic compound as well as a use method and application thereof. The compound is a compound as shown in a formula (I) or stereoisomers, stereomers, tautomers, nitric oxides, solvates, metabolites and pharmaceutically acceptable salts or prodrugs of the compound as shown in the formula (I). The invention further provides a medicament composition containing the compound. The compound and the medicament composition are capable of regulating the activity of protein kinase in a biological sample body and are used for protecting, treating or relieving proliferative diseases of patients. The formula (I) is as shown in the specification.