1258850-50-8 Usage
General Description
6-(4-Chlorophenyl)pyrazine-2-carboxylic acid is a chemical compound that belongs to the class of pyrazine carboxylic acids. It is an organic compound with the molecular formula C11H7ClN2O2 and a molecular weight of 232.636 g/mol. 6-(4-Chlorophenyl)pyrazine-2-carboxylic Acid is a derivative of pyrazine and contains a carboxylic acid functional group and a 4-chlorophenyl group. It is often used in the pharmaceutical industry for the synthesis of various drugs and pharmaceutical products. Additionally, it has been found to exhibit antimicrobial and antifungal properties, making it a potentially useful compound in the development of new antibiotics and antifungal agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1258850-50-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,8,8,5 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1258850-50:
(9*1)+(8*2)+(7*5)+(6*8)+(5*8)+(4*5)+(3*0)+(2*5)+(1*0)=178
178 % 10 = 8
So 1258850-50-8 is a valid CAS Registry Number.
1258850-50-8Relevant articles and documents
Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Nav1.8 sodium channel with efficacy in a model of neuropathic pain
Scanio, Marc J.C.,Shi, Lei,Drizin, Irene,Gregg, Robert J.,Atkinson, Robert N.,Thomas, James B.,Johnson, Matthew S.,Chapman, Mark L.,Liu, Dong,Krambis, Michael J.,Liu, Yi,Shieh, Char-Chang,Zhang, Xufeng,Simler, Gricelda H.,Joshi, Shailen,Honore, Prisca,Marsh, Kennan C.,Knox, Alison,Werness, Stephen,Antonio, Brett,Krafte, Douglas S.,Jarvis, Michael F.,Faltynek, Connie R.,Marron, Brian E.,Kort, Michael E.
experimental part, p. 7816 - 7825 (2011/02/22)
Nav1.8 (also known as PN3) is a tetrodotoxin-resistant (TTx-r) voltage-gated sodium channel (VGSC) that is highly expressed on small diameter sensory neurons. It has been implicated in the pathophysiology of inflammatory and neuropathic pain, a
