1258865-68-7Relevant articles and documents
Synthesis of epoxy and aziridino malonyl peptidomimetics
Fioravanti, Stefania,Gasbarri, Simona,Pellacani, Lucio,Ramadori, Federico,Tardella, Paolo A.
, p. 9401 - 9404 (2010)
Short malonyl dehydro peptides have been epoxidized using H 2O2/Na2WO4 dihydrate. The obtained diastereomeric epoxides were separated by HPLC and successfully tested in the ring opening reaction with N-Boc l-cysteine methyl ester, to indicate their electrophilic behavior. Moreover, by a simple two-step reaction, the epoxy malonyl peptides can be converted into the corresponding aziridino malonyl peptides.
