1258873-82-3

Basic information

• Product Name: C₂₀H₁₇N₃O₂S₂
• Synonyms: C₂₀H₁₇N₃O₂S₂
• CAS NO: 1258873-82-3
• Molecular Weight: 395.506
• Mol File: 1258873-82-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₇N₃O₂S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₇N₃O₂S₂(1258873-82-3)
• EPA Substance Registry System: C₂₀H₁₇N₃O₂S₂(1258873-82-3)

Safety Data

• Hazardous Substances Data: 1258873-82-3(Hazardous Substances Data)

Upstream product

• 7357-70-2 Cyanothioacetamide 
• 103-72-0 phenyl isothiocyanate 
• 28940-11-6 7-methyl-3,4-dihydro-2H-1,5-benzodioxepin-3-one 

Relevant articles and documents

Diversity-oriented synthesis of spiro-substituted 1,3-thiazine library via a one-pot, two-step, three-component reaction

A sequential one-pot, two-step, three-component reaction for efficient synthesis of spiro-substituted 1,3-thiazine library has been developed. The syntheses were achieved by reacting cyanoacetamide with isothiocyanate derivatives to give rise to 2-cyano-3-mercaptoacrylamides, which are trapped in situ by various cycloketones through cyclization, providing multifunctionalized spiro-substituted 1,3-thiazine analogues. This procedure features short reaction time, generally good to excellent yields, easily available starting materials, and operational simplicity. This chemistry provides an efficient and promising synthetic strategy to diversity-oriented construction of the 1,3-thiazine skeleton.