1258940-00-9 Usage
General Description
(S)-3-phenyl piperidine, also known as (+)-cis-N-Methyl-3-phenylpiperidine, is a chemical compound with the molecular formula C12H17N. It is a chiral intermediate used in the synthesis of various pharmaceutical compounds, including analgesics and antipsychotic medications. The compound is a piperidine derivative with a phenyl group attached to the third carbon atom, and its chiral nature makes it useful in the production of enantiopure drugs. (S)-3-phenyl piperidine is also used as a building block in organic synthesis for the creation of diverse chemical compounds. Due to its versatile applications in the pharmaceutical and chemical industries, (S)-3-phenyl piperidine is a valuable compound for drug development and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 1258940-00-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,8,9,4 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1258940-00:
(9*1)+(8*2)+(7*5)+(6*8)+(5*9)+(4*4)+(3*0)+(2*0)+(1*0)=169
169 % 10 = 9
So 1258940-00-9 is a valid CAS Registry Number.
1258940-00-9Relevant articles and documents
Asymmetric synthesis of chiral N-sulfinyl 3-alkyl- and 3-arylpiperidines by α-alkylation of N-sulfinyl imidates with 1-chloro-3-iodopropane
Colpaert, Filip,Mangelinckx, Sven,De Kimpe, Norbert
, p. 234 - 244 (2011/03/19)
α-Alkylation of N-sulfinyl imidates with 1-chloro-3-iodopropane successfully led to 2-substituted N-tert-butanesulfinyl-5-chloropentanimidates in acceptable diastereomeric ratios (dr 67/33 to 72/28) and good yields (74-86%). Subsequent reduction with NaBH4 led to the corresponding 2-substituted N-tert-butanesulfinyl-5-chloropentylamines, which could be cyclized to a range of new chiral 3-substituted N-tert-butanesulfinylpiperidines using NaH in DMSO. Finally, the N-tert-butanesulfinylpiperidines could be efficiently deprotected to enantiomerically pure 3-alkyl- and 3-arylpiperidine hydrochlorides.
