1258977-05-7

Basic information

• Product Name: 2-ChloroMethyl-6-hydroxy-1H-quinazolin-4-one
• Synonyms: 2-ChloroMethyl-6-hydroxy-1H-quinazolin-4-one;2-(CHLOROMETHYL)-6-HYDROXYQUINAZOLIN-4(3H)-ONE
• CAS NO: 1258977-05-7
• Molecular Formula: C9H7ClN2O2
• Molecular Weight: 210.61708
• EINECS: -0
• Mol File: 1258977-05-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: >250 °C
• Boiling Point: 436.1±55.0 °C(Predicted)
• Appearance: /
• Density: 1.57±0.1 g/cm3(Predicted)
• PKA: 9.26±0.20(Predicted)
• CAS DataBase Reference: 2-ChloroMethyl-6-hydroxy-1H-quinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ChloroMethyl-6-hydroxy-1H-quinazolin-4-one(1258977-05-7)
• EPA Substance Registry System: 2-ChloroMethyl-6-hydroxy-1H-quinazolin-4-one(1258977-05-7)

Safety Data

• Hazardous Substances Data: 1258977-05-7(Hazardous Substances Data)

Upstream product

• 394-31-0 2-amino-5-hydroxybenzoic acid 
• 107-14-2 chloroacetonitrile 

Relevant articles and documents

A General synthetic procedure for 2-chloromethyl-4(3H)-quinazolinone derivatives and their utilization in the preparation of novel anticancer agents with 4-anilinoquinazoline scaffolds

In our ongoing research on novel anticancer agents with 4-anilinoquinazoline scaffolds, a series of novel 2-chloromethyl-4(3H)- quinazolinones were needed as key intermediates. An improved one-step synthesis of 2-chloromethyl-4(3H)-quinazolinones utilizin