1259034-35-9

Basic information

• Product Name: TERT-BUTYL 3-ETHYNYL-3-HYDROXYAZETIDINE-1-CARBOXYLATE
• Synonyms: TERT-BUTYL 3-ETHYNYL-3-HYDROXYAZETIDINE-1-CARBOXYLATE;1-Boc-3-ethynyl-3-hydroxyazetidine
• CAS NO: 1259034-35-9
• Molecular Formula: C₁₀H₁₅NO₃
• Molecular Weight: 197.231
• Mol File: 1259034-35-9.mol

Chemical Properties

• Boiling Point: 273.2±40.0 °C(Predicted)
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 12.20±0.20(Predicted)
• CAS DataBase Reference: TERT-BUTYL 3-ETHYNYL-3-HYDROXYAZETIDINE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 3-ETHYNYL-3-HYDROXYAZETIDINE-1-CARBOXYLATE(1259034-35-9)
• EPA Substance Registry System: TERT-BUTYL 3-ETHYNYL-3-HYDROXYAZETIDINE-1-CARBOXYLATE(1259034-35-9)

Safety Data

• Hazardous Substances Data: 1259034-35-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
TERT-BUTYL 3-ETHYNYL-3-HYDROXYAZETIDINE-1-CARBOXYLATE is used as a chemical intermediate for the synthesis of pharmaceuticals, specifically antibiotics. Its unique structure, which includes an ethynyl, hydroxy, and carboxylate group, makes it a valuable component in the development of new drugs.
Used in Organic Chemistry Research:
In the field of organic chemistry, TERT-BUTYL 3-ETHYNYL-3-HYDROXYAZETIDINE-1-CARBOXYLATE is used as a research compound to study the properties and reactions of azetidines. Its tert-butyl functional group and other structural features provide opportunities for exploring various chemical reactions and transformations.

Upstream product

• 398489-26-4 tert-butyl 3-oxoazetidine-1-carboxylate 

Downstream Products

• 1349199-61-6 tert-butyl 3-oxo-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate 
• 1349199-63-8 tert-butyl 3-hydroxy-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate 
• 1446099-95-1 (E)-tert-butyl 3-(2-(dimethyl(phenyl)silyl)vinyl)-3-hydroxyazetidine-1-carboxylate 

Relevant articles and documents

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers and pharmaceutically acceptable salts and esters thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

Expanding the azaspiro[3.3]heptane family: Synthesis of novel highly functionalized building blocks

The preparation of versatile azaspiro[3.3]heptanes carrying multiple exit vectors is disclosed. Expedient synthetic routes enable the straightforward access to these novel modules that are expected to have significance in drug discovery and design.

CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1

This invention relates to novel compounds of the Formula (I), (II), (II-A), (Il-B), (ll-C), (ll-D), (III). (III-A). (IIIl-B). (IIl-C). (IIl-D), (III-E) (IV), (IV-A), (IV-B). (IV-C), (IV-D). (V), (V-A), (V-B), (V-C), (V-D), pharmaceutically acceptable salt