1259056-34-2

Basic information

• Product Name: tert-butyl 4-cyanoazepane-1-carboxylate
• Synonyms: tert-butyl 4-cyanoazepane-1-carboxylate;4-Cyano-azepane-1-carboxylic acid tert-butyl ester;1-Boc-azepane-4-carbonitrile
• CAS NO: 1259056-34-2
• Molecular Formula: C12H20N2O2
• Molecular Weight: 224.2994
• EINECS: -0
• Mol File: 1259056-34-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 342.3±35.0 °C(Predicted)
• Appearance: /
• Density: 1.05±0.1 g/cm3(Predicted)
• PKA: -2.73±0.40(Predicted)
• CAS DataBase Reference: tert-butyl 4-cyanoazepane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-cyanoazepane-1-carboxylate(1259056-34-2)
• EPA Substance Registry System: tert-butyl 4-cyanoazepane-1-carboxylate(1259056-34-2)

Safety Data

• Hazardous Substances Data: 1259056-34-2(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-cyanoazepane-1-carboxylate is a chemical compound with the molecular formula C12H19NO2. It is a tertiary butyl ester derivative of 4-cyanoazepane-1-carboxylic acid. tert-butyl 4-cyanoazepane-1-carboxylate is commonly used in organic synthesis and pharmaceutical research. It can be used as a building block in the synthesis of various bioactive molecules and pharmaceutical compounds. Tert-butyl 4-cyanoazepane-1-carboxylate is also known for its potential as a drug candidate in medicinal chemistry due to its unique structural features and biological activities. Additionally, it has been studied for its potential pharmacological properties and therapeutic applications.

Upstream product

• 188975-88-4 tert-butyl 4-oxoazepane-1-carboxylate 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 

Downstream Products

• 868284-36-0 (rac)-1-(tert-butoxycarbonyl)azepane-4-carboxylic acid 
• 1369353-14-9 tert-butyl 4-(aminomethyl)azepane-1-carboxylate 

Relevant articles and documents

INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF

Compounds and methods for their preparation and use as therapeutic or prophylactic agents, for example for treatment of cancer, bacterial or viral diseases by targeting Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1).

METALLO-BETA-LACTAMASE INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to metallo-β-lactamase inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-β-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more β-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.