1259059-68-1

Usage

Uses

Used in Pharmaceutical Research:
1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one is used as a building block or intermediate in pharmaceutical research for its potential application in the treatment of various medical conditions.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one is used as a valuable intermediate due to its versatile reactivity.
Used in Antimicrobial Applications:
1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one is used as an antimicrobial agent for its potential to treat various infections.
Used in Anticonvulsant Applications:
1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one is used as an anticonvulsant in the development of medications aimed at controlling seizures and epilepsy.
Used in Antitumor Applications:
1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one is used as an antitumor agent, being investigated for its potential role in the treatment of cancer.
Used in Modulating Biological Processes:
In drug discovery and development, 1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one is used to modulate different biological processes such as apoptosis and cell proliferation, making it a valuable tool for creating new therapeutics.

Upstream product

• 288-94-8 1H-tetrazole 
• 5000-66-8 2-chlorophenacyl bromide 

Downstream Products

• 913088-80-9 carbamic acid (R)-1-(2-chlorophenyl)-2-(tetrazol-2-yl)ethyl ester 
• 1259059-71-6 1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-2-yl)ethan-1-one 

Relevant academic research and scientific papers

Method for preparing aryl 2-tetrazol-2-yl ketone with improved selectivity

The present disclosure relates to a method for preparing aryl 2-tetrazol-2-yl ketone of the following Formula 1a with improved selectivity: wherein R1 and R2 are the same as defined herein.

METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER

Disclosed is a method for the preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester, comprising the enantioselective enzyme reduction of the corresponding arylketone and the carbamation of the resultant alcohol.

METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER

Disclosed is a method for the preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester, comprising the asymmetric reduction of arylketone and the carbamation of alcohol.

METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER

Disclosed is a method for the preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester, comprising the asymmetric reduction of arylketone and the carbamation of alcohol.

NEUROTHERAPEUTIC AZOLE COMPOUNDS

Azole compounds containing carbamoyl group and pharmaceutically useful salts thereof are described. The compounds are effective anticonvulsants which are used in the treatment of disorders of the central nervous system, especially as anxiety, depression, convulsion, epilepsy, migraine, bipolar disorder, drug abuse, smoking, ADHD, obesity, sleep disorder, neuropathic pain, stroke, cognitive impairment, neurodegeneration, stroke and muscle spasm.