1259075-13-2Relevant academic research and scientific papers
Synthetic studies on the mycolactone core
Ko, Kwang-Seuk,Alexander, Matthew D.,Fontaine, Shaun D.,Biggs-Houck, James E.,La Clair, James J.,Burkart, Michael D.
, p. 5159 - 5165 (2010)
Two approaches are presented for the synthesis of the macrolide core of the mycolactone polyketides. The first intertwines ring closing metathesis (RCM) within a two-step Julia olefination protocol, while the second intercepts the optimized routes of Kishi, thereby providing formal access to the mycolactones.
