1259115-41-7Relevant academic research and scientific papers
Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa
Hanessian, Stephen,Larsson, Andreas,Fex, Tomas,Knecht, Wolfgang,Blomberg, Niklas
scheme or table, p. 6925 - 6928 (2011/02/22)
The synthesis of a series of novel macrocyclic compounds designed to target blood coagulation Factor XIa is described. The compounds were evaluated for their inhibition of a small set of serine proteases. Several compounds displayed modest activity and go
